Les publications de l’équipe TRANSAT :


Migeotte I., Riboldi E., FranssenJ.D., Grégoire F., Loison C., Wittamer V., Detheux M., Robberecht P., Costagliola S., Vassart G., Sozzani S., Parmentier M., CommuniD. Identification and characterization of an endogenous chemotactic ligand specific for FPRL2. J Exp Med., 201,83-93, 2005.



Nony P., Gaude H., Rossel M., Fournier L., Rouault J. P. and Billaud M. Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37. Oncogene , 22,9165-9175, 2003.



Le Poul E., Loison C., Struyf S., Springael J.Y., Lannoy V., Decobecq M.E., Brezillon S., Dupriez V., Vassart G., Van Damme J., Parmentier M. and DetheuxM., Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation. JBC, 278, 25481-25489, 2003.



Zhu B., Chappuis-Flament S., Wong E., Jensen I., Gumbiner B.M., Leckband D. Functional analysis of the structural basis of homophilic cadherine adhesion. Biophys. J., 84(6):4033-42, 2003.



Nony P., Chadeuf G., Tessier J., Moullier P. and Salvetti A. Evidence for packaging of rep-cap sequences into adeno-associated virus (AAV) type 2 capsids in the absence of the inverted terminal repeats: a model for generation of rep-positive AAV particles. J. Virol., 77: 776-781, 2003.



Boggon T. J., Murray J., Chappuis-Flament S., Wong E., Gumbiner B. M., Shapiro L. Structure of the C-cadherin ectodomain and implications for the mechanism of cell adhesion. Science, 296(5571):1308-13, 2002.



Salvatore G, Nagata S, Billaud M, Santoro M, Vecchio G, Pastan I. Generation and characterization of novel monoclonal antibodies to the Ret receptor tyrosine kinase. Bioch. Biophys. Res. Comm., 21:813-817, 2002.



Nony P., Tessier J., Chadeuf G., Ward P., Giraud A., Dugast M., Linden R.M., Moullier P. and Salvetti A. A novel cis-acting replication element in the adeno-associated virus type 2 genome is involved in the amplification of integrated rep-cap sequences. J. Virol. 75 : 9991-9994, 2001.



Chappuis-Flament S., Wong E., Hicks L. D., Kay C. M., Gumbiner B. M. Role of cadherin extracellular repeats in adhesive function. J. Cell Biol., 154(1):231-243, 2001.



Manié S, Santoro M, Fusco A, Billaud M. The RET receptor: function in development and dysfunction in congentital malformation. Trends Genet., 17:549-608, 2001.



Mellilo RM, Santoro M, Ong SH, Billaud M, Fusco A, Schlessinger J, Lax I. The docking protein FRS2 links RET and its oncogenic forms with the Ras/MAPK cascade. Mol. Cell. Biol., 21:4177-4187, 2001.



Mellilo RM, De Vita G, Carlomagno F, Formisano P, Vecchio G, Fusco A, Billaud M, Santoro M. The Insulin Receptor Substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to RET : evidence for a competition between Shc and IRS-1 for the binding to RET. Oncogene, 20:209-218, 2001.



Forcet C., Granger L., Corset V., Poulat M., Billaud M., Bredesen DE., Edery P., Mehlen P. The RET proto-oncogene induces apoptosis : a novel mechanism for Hirschsprung disease. EMBO J., 19:4056-4063, 2000.



De Vita G., Melillo RM., Carlomagno F., Visconti R., Castellone MD., Bellacosa A., Billaud M., Fusco A., Tsichlis PN., Santoro M. Tyrosine 1062 of RET-MEN2A mediates activation of AKT(PKB) and MAPK pathways leading to PC12 survival. Cancer Res., 60:3727-3731, 2000.



Prioleau M.-N., Nony P., Simpson M. and Felsenfeld G. An insulator element and condensed chromatin region separate the chicken _-globin locus from an independently regulated erythroid specific folate receptor gene. EMBO J., 18:4035-4048, 1999.



Chappuis-Flament S., Pasini A., De Vita G., Ségouffin-Cariou, C., Fusco A., Attié T., Lenoir, GM., Santoro M., Billaud M. Dual effect on the RET receptor of MEN 2 mutations affecting specific extracytoplasmic cysteines. Oncogene, 17:2851-2861, 1998.



Bouey-Bencteux E., Loison C., Pommery N., Houssin R. & Hénichart J.P. Synthesis and antiproliferative properties of 4-aminoquinazoline derivatives as inhibitors of EGF-receptor-associated tyrosine kinase activity Anti-Cancer Drug Des., 17:2851-2861, 1998.



Nony P., Hannon R., Gould H. and Felsenfeld G. Alternate promoters and developmental modulation of expression of the chicken GATA-2 gene in hematopoietic progenitor cells. J. Biol. Chem., 13,893-922, 1998.



Pelet A., Geneste O., Edery P., Chappuis-Flament S., Pasini A., Attié T., Munnich A., Lenoir G., Lyonnet S., Billaud M. Various mechanisms cause RET-mediated signaling defects in Hirschsprung disease. J. Clin. Invest., 101:1415-1423, 1998.



Michiels F-M., Chappuis S., Caillou B., Pasini A., Talbot M., Monier R., Lenoir G. M. Feunteun J., Billaud M. Development of medullary thyroid carcinoma in transgenic mice expressing the RET proto-oncogene alterd by a multiple endocrine neoplasia type 2A mutation. Proc. Natl. Acad. Sci. USA, 94 :3330-35, 1997.



Pedone P.V., Omichinski J.G., Nony P., Trainor C., Gronenborn A.M., Clore G.M. and Felsenfeld G. The N-terminal fingers of cGATA-2 and cGATA-3 are independant sequence-specific DNA binding domains. EMBO J., 16:2874-82, 1997.



Rossel M., Pasini A., Chappuis S., Geneste O., Fournier L., Schuffenecker I., Takahashi M., van Grunsven L., Urdiales, J. L., Rudkin B. B. R., Lenoir G. M., Billaud M. Distinct properties of two RET isoforms activated by MEN 2A/FMTC and MEN 2B mutations. Oncogene, 15 :393-402, 1997.



Pasini A., Michiels FM., Chappuis-Flament S., Geneste O., Rossel M., Fournier L., Feunteun J., Lenoir G., Schuffenecker I., Billaud M. Crête neurale et polyendocrinoptahies. C. R. Soc. Biol., 190:557-567, 1996.



Chappuis S., Geneste O., Pasini A., Lenoir G. M., Billaud M. RET et GDNF: un récepteur orphelin trouve une famille nourricière. Médecine sciences, 12:1408-1413, 1996.



Nony P., Prudhomme J.C. and Couble P. Regulation of the P25 gene transcription in the silk gland of Bombyx mori. Biol. Cell., 84:43-52, 1995.


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